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Article

Phospho-mimicking Atf1 mutants bypass the transcription activating function of the MAP kinase Sty1 of fission yeast.

Current genetics - 1 Feb 2018

Sánchez-Mir Laura, Salat-Canela Clàudia, Paulo Esther, Carmona Mercè, Ayté José, Oliva Baldo, Hidalgo Elena

Abstract excerpt

Stress-dependent activation of signaling cascades is often mediated by phosphorylation events, but the exact nature and role of these phosphorelays are frequently poorly understood. Here, we review which are the consequences of the stress-dependent phosphorylation of a transcription factor on gene activation. In fission yeast, the MAP kinase Sty1 is activated upon several environmental hazards and promotes cell...

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Share to Gene Expression Regulation, Fungal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28799013
DOI: 10.1007/s00294-017-0730-7

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