Article
Hereditary prostate cancer as a feature of Lynch syndrome.
Familial cancer - 1 Mar 2011
Bauer Christina M, Ray Anna M, Halstead-Nussloch Bronwen A, Dekker Robert G, Raymond Victoria M, Gruber Stephen B, Cooney Kathleen A
Abstract excerpt
Lynch Syndrome is an autosomal dominant condition characterized by early onset colorectal cancer (CRC) and is associated with cancers of the gastrointestinal and reproductive tracts. Germline mutations in DNA mismatch repair (MMR) genes have been causally associated with cancers of Lynch Syndrome. We investigated the occurrence of prostate cancer (PCa) in families with a history of colorectal cancer to assess...
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