Article
Low frequency of microsatellite instability in hereditary prostate cancer.
BJU international - 1 Mar 2001
Ahman A K, Jonsson B A, Damber J E, Bergh A, Grönberg H
Abstract excerpt
OBJECTIVE: To investigate whether there is widespread microsatellite instability (MSI) in families with hereditary prostate cancer (HPC). PATIENTS AND METHODS: Eighty-four prostate tumours from 80 Swedish men in 35 families with HPC were screened for genetic instability at microsatellite marker loci BAT-25, BAT-26, BAT-34C4, D2S123 and D17S250. RESULTS: MSI was detected in only five individuals from different...
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