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Article

The spectrum of urological malignancy in Lynch syndrome.

Familial cancer - 1 Mar 2013

Barrow P J, Ingham S, O'Hara C, Green K, McIntyre I, Lalloo F, Hill J, Evans D G

Abstract excerpt

Urological tumours are the third most frequent malignancy in Lynch syndrome after colonic and endometrial cancer. Upper urinary tract tumours are well recognised in Lynch syndrome, but the association with prostate and bladder cancer is controversial. We determined the incidence and cumulative and relative risks of prostate and bladder cancer in a cohort of Lynch syndrome families. Male Lynch syndrome mutation...

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Source

Identifiers

PMID: 23054215
DOI: 10.1007/s10689-012-9573-z

Genes

MSH2
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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