Article
BDNF val66met polymorphism affects aging of multiple types of memory.
Brain research - 1 Jul 2015
Kennedy Kristen M, Reese Elizabeth D, Horn Marci M, Sizemore April N, Unni Asha K, Meerbrey Michael E, Kalich Allan G, Rodrigue Karen M
Abstract excerpt
The BDNF val66met polymorphism (rs6265) influences activity-dependent secretion of brain-derived neurotrophic factor in the synapse, which is crucial for learning and memory. Individuals homozygous or heterozygous for the met allele have lower BDNF secretion than val homozygotes and may be at risk for reduced declarative memory performance, but it remains unclear which types of declarative memory may be affected...
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