Article
ERCC2, ERCC1 polymorphisms and haplotypes, cooking oil fume and lung adenocarcinoma risk in Chinese non-smoking females.
Journal of experimental & clinical cancer research : CR - 14 Dec 2009
Yin Zhihua, Su Meng, Li Xuelian, Li Mingchuan, Ma Rui, He Qincheng, Zhou Baosen
Abstract excerpt
BACKGROUND: Excision repair cross-complementing group 1 (ERCC1) and group 2 (ERCC2) proteins play important roles in the repair of DNA damage and adducts. Single nucleotide polymorphisms (SNPs) of DNA repair genes are suspected to influence the risk of lung cancer. This study aimed to investigate the association between the ERCC2 751, 312 and ERCC1 118 polymorphisms and the risk of lung adenocarcinoma in Chinese...
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