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Article

Characterization of functional excision repair cross-complementation group 1 variants and their association with lung cancer risk and prognosis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2008

Yu Dianke, Zhang Xuemei, Liu Ju, Yuan Peng, Tan Wen, Guo Yongli, Sun Tong, Zhao Dan, Yang Ming, Liu Junniao, Xu Binghe, Lin Dongxin

Abstract excerpt

PURPOSE: The excision repair cross-complementation group 1 (ERCC1) plays a pivotal role in DNA repair and has been linked to protection against carcinogenesis and resistance to platinum-based anticancer drugs. We tested whether genetic variants in the ERCC1 gene are associated with susceptibility...

Read the complete abstract on PubMed

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Share to Antineoplastic Agents
Share to Carcinoma, Small Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to DNA Repair

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Share to Linkage Disequilibrium

Share to Lung Neoplasms

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Source

Identifiers

PMID: 18451256
DOI: 10.1158/1078-0432.CCR-07-1612

Genes

ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18451256-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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