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Article

STAT1 is required for redifferentiation during Madin-Darby canine kidney tubulogenesis.

Molecular biology of the cell - 15 Nov 2010

Kim Minji, O'Brien Lucy Erin, Kwon Sang-Ho, Mostov Keith E

Abstract excerpt

Tubule formation in vitro using Madin-Darby canine kidney (MDCK) epithelial cells consists mainly of two processes. First, the cells undergo a partial epithelial-mesenchymal transition (pEMT), losing polarity and migrating. Second, the cells redifferentiate, forming cords and then tubules with continuous lumens. We have shown previously that extracellular signal-regulated kinase activation is required for pEMT....

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Source

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Identifiers

PMID: 20861313
DOI: 10.1091/mbc.E10-02-0112
PMCID: PMC2982126

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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