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Article

Phenotypic transition of the collecting duct epithelium in congenital urinary tract obstruction.

Journal of biomedicine & biotechnology - 1 Jan 2010

Trnka Peter, Hiatt Michael J, Ivanova Larissa, Tarantal Alice F, Matsell Douglas G

Abstract excerpt

Epithelial-mesenchymal transition (EMT) has emerged in recent years as an important process in the development of organ fibrosis in many human diseases. Our previous experience in a nonhuman primate model of obstructive nephropathy suggested that EMT of collecting duct epithelium contributes to the development of interstitial fibrosis. In this study we demonstrate for the first time in humans that obstructed...

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Identifiers

PMID: 20037736
DOI: 10.1155/2010/696034
PMCID: PMC2796364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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