Article
Identification and characterization of mesenchymal-epithelial progenitor-like cells in normal and injured rat liver.
The American journal of pathology - 1 Jan 2015
Liu Daqing, Yovchev Mladen I, Zhang Jinghang, Alfieri Alan A, Tchaikovskaya Tatyana, Laconi Ezio, Dabeva Mariana D
Abstract excerpt
In normal rat liver, thymocyte antigen 1 (Thy1) is expressed in fibroblasts/myofibroblasts and in some blood progenitor cells. Thy1-expressing cells also accumulate in the liver during impaired liver regeneration. The origin and nature of these cells are not well understood. By using RT-PCR analysis and immunofluorescence microscopy, we describe the presence of rare Thy1(+) cells in the liver lobule of normal...
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