Article
Genetic and diabetic auto-antibody markers in Saudi children with type 1 diabetes.
Human immunology - 1 Dec 2010
Manan Hakbany, Angham Al Mutair, Sitelbanat Awadalla
Abstract excerpt
Human leukocyte antigen DRB1 and DQB1 contribute to the genetic susceptibility of type 1 diabetes (T1DM), and they are involved in the induction of the autoimmune destruction of pancreatic beta cells precipitating the disease. The objective of this study was to examine diabetic auto-antibodies (ICA-512, GAD65) and the HLA-DR/DQ genotype among T1DM Saudi children in a cross-sectional study conducted at King Khalid...
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