Polymorphisms of HLA class II predispose children and adolescents with type 1 diabetes mellitus to autoimmune thyroid disease.

doi:10.1080/0891693031000101279

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Article

Polymorphisms of HLA class II predispose children and adolescents with type 1 diabetes mellitus to autoimmune thyroid disease.

Autoimmunity - 1 May 2003

Kim Eun Young, Shin Choong Ho, Yang Sei Won

Abstract excerpt

To determine the prevalence of autoimmune thyroid disease (AITD) in children and adolescents with type 1 diabetes mellitus (DM), and assess whether the development of AITD is correlated with specific DQ-A and DQ-B loci of the HLA class II antigens, we analyzed thyroid function using anti-thyroid antibodies and HLA-DQ-A and -DQ-B polymorphisms in 69 patients with type 1 DM, in 75 normal healthy controls, and in 21...

Topics

Adolescent
Adult
Autoimmune Diseases
Diabetes Mellitus, Type 1
Female
Genetic Predisposition to Disease
HLA-DQ Antigens
Humans
Male
Polymorphism, Genetic
Thyroid Diseases

Source

Open in PubMed

Identifiers

PMID: 12911285
DOI: 10.1080/0891693031000101279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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