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Article

[Genetic and humoral autoimmunity markers of type 1 diabetes: from theory to practice].

Arquivos brasileiros de endocrinologia e metabologia - 1 Mar 2008

Silva Maria Elizabeth Rossi da, Mory Denise, Davini Elaine

Abstract excerpt

Type 1 A diabetes mellitus (T1AD) results from the autoimmune destruction of the insulin producing pancreatic beta-cells. The largest contribution to genetic susceptibility comes from several genes located in the major histocompatibility complex on chromosome 6p21.3 (IDDM1 locus), accounting for at least 40% of the family aggregation of this disease. The highest-risk human leukocyte antigen HLA genotype for T1AD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18438527
DOI: 10.1590/s0004-27302008000200004

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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