Article
Association of HLA-DRB1 and -DQB1 alleles with type 1 (autoimmune) diabetes in African Arabs: systematic review and meta-analysis.
Immunological investigations - 1 Feb 2019
Hajjej Abdelhafidh, Almawi Wassim Y, Stayoussef Mouna, Arnaiz-Villena Antonio, Hattab Lasmar, Hmida Slama
Abstract excerpt
Several studies confirmed the association of HLA-DRB1 and -DQB1 alleles with altered risk of type 1 diabetes (T1D). However, data from individual studies based on small sample sizes yielded often conflicting findings in African Arabs. This is a systematic review and meta-analysis aimed at comprehensively evaluating this association with T1D, using molecular HLA data. Relevant studies were identified through...
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