Article
Glutamic acid decarboxylase 65 and islet cell antigen 512/IA-2 autoantibodies in relation to human leukocyte antigen class II DR and DQ alleles and haplotypes in type 1 diabetes mellitus.
Clinical and vaccine immunology : CVI - 1 Jun 2011
Stayoussef Mouna, Benmansour Jihen, Al-Jenaidi Fayza A, Said Hichem B, Rayana Chiheb B, Mahjoub Touhami, Almawi Wassim Y
Abstract excerpt
The frequencies of autoantibodies against glutamic acid decarboxylase 65 (GAD65) and islet cell antigen (ICA) 512/IA-2 (512/IA-2) are functions of the specific human leukocyte antigen (HLA) in type 1 diabetes mellitus (T1D). We investigated the association of HLA class II (DR and DQ) alleles and haplotypes with the presence of GAD and IA-2 autoantibodies in T1D. Autoantibodies were tested in 88 Tunisian T1D...
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