Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autologous tumor-specific cytotoxic T-lymphocytes in a child with neuroblastoma.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jan 1990

Azuma E, Hanada M, Masuda S I, Komada Y, Sakurai M

Abstract excerpt

Activation of peripheral blood lymphocytes from a neuroblastoma patient by co-cultivation with autologous neuroblastoma cells in a mixed lymphocyte-tumor cell culture (A-MLTC) resulted in the generation of cytotoxic activity against the autologous neuroblastoma cell line HNB-MS. A-MLTC was set up in the presence of recombinant human interleukin-2 (IL-2). HNB-MS stimulator was treated with recombinant human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Cell Line, Transformed
Share to TNF gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neuroblastoma

Share to Phenotype

Share to Receptors, Interleukin-2

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 2085662
DOI: 10.1016/0753-3322(90)90168-9

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autologous tumor-specific cytotoxic T-lymphocytes in a child with neuroblastoma.PMID 2085662Read ↗

The microenvironment of human neuroblastoma supports the activation of tumor-associated T lymphocytesSemantic proximity Read ↗

Autologous tumor cell killing activity of tumor-associated lymphocytes in patients with head and neck carcinomas.Semantic proximity Read ↗

Interleukin-2 gene-modified allogeneic tumor cells for treatment of relapsed neuroblastoma.Semantic proximity Read ↗

Cytotoxicity of lymphokine-activated killer cells against human neuroblastoma cells: modulation by neuroblast differentiation.Semantic proximity Read ↗

Autologous tumour-specific cytotoxic T-cell clone established from tumour-infiltrating lymphocytes (TIL) of malignant ascites in the absence of recombinant interleukin 2(rIL2): activation by autologous tumour cell alone.Semantic proximity Read ↗

Natural interleukin-2 and lymphokine activated killer cells in the treatment of neuroblastoma in vitro and in vivo.Semantic proximity Read ↗

Soluble factors released by activated cytotoxic T lymphocytes interfere with death receptor pathways in neuroblastoma.Semantic proximity Read ↗

Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysisSemantic proximity Read ↗

Cytolytic potential of peripheral blood T-lymphocytes following adoptive immunotherapy with lymphokine-activated killer cells and low-dose interleukin 2.Semantic proximity Read ↗

Sustained cytokine production and immunophenotypic changes in human neuroblastoma cell lines transduced with a human gamma interferon vector.Semantic proximity Read ↗

Composite response of naive T cells to stimulation with the autologous lymphoblastoid cell line is mediated by CD4 cytotoxic T cell clones and includes an Epstein-Barr virus-specific component.Semantic proximity Read ↗

Preclinical studies for adoptive immunotherapy in bone marrow transplantation. Generation of anti-CD3 activated cytotoxic T cells from normal donors and autologous bone marrow transplant candidates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.