Cytolytic potential of peripheral blood T-lymphocytes following adoptive immunotherapy with lymphokine-activated killer cells and low-dose interleukin 2.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Cytolytic potential of peripheral blood T-lymphocytes following adoptive immunotherapy with lymphokine-activated killer cells and low-dose interleukin 2.

Cancer research - 1 Mar 1991

Yoshino I, Yano T, Murata M, Ishida T, Sugimachi K, Kimura G, Nomoto K

Abstract excerpt

In this study, we investigated the cytolytic activity of peripheral blood T-cells (PBT) obtained from nine patients with primary lung cancer treated by surgical adjuvant adoptive immunotherapy (AIT) with lymphokine-activated killer cells and low-dose recombinant interleukin 2 at the time of rebound lymphocytosis (24-48 h after AIT). In eight of nine patients, nonspecific cytotoxicity of peripheral blood...

Topics

Aged
Cytotoxicity, Immunologic
Female
Humans
Immunotherapy, Adoptive
Interleukin-2
Killer Cells, Lymphokine-Activated
Lymphocyte Activation
Male
Membrane Glycoproteins
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Neoplasms

Perforin

Phenotype

Pore Forming Cytotoxic Proteins

T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 1997188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1997188-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytolytic potential of peripheral blood T-lymphocytes following adoptive immunotherapy with lymphokine-activated killer cells and low-dose interleukin 2.PMID 1997188Read ↗

Cytolytic effector cells against human tumors: distinguishing phenotype and function.Semantic proximity Read ↗

Prospects for Combined Treatment of Non-Small Cell Lung Cancer Using Autologous Activated LymphocytesSemantic proximity Read ↗

OK-432 develops CTL and LAK activity in mononuclear cells from regional lymph nodes of lung cancer patients.Semantic proximity Read ↗

Establishment of an immortalized T-cell line from lung cancer tissue: phenotypic and functional analyses.Semantic proximity Read ↗

Autologous tumor killing activity as a prognostic factor in primary resected nonsmall cell carcinoma of the lung.Semantic proximity Read ↗

Expansion of tumor-infiltrating lymphocytes in non-small cell lung cancer: Clinical potential and efficacy in EGFR mutation subsets.Semantic proximity Read ↗

Preclinical studies for adoptive immunotherapy in bone marrow transplantation. Generation of anti-CD3 activated cytotoxic T cells from normal donors and autologous bone marrow transplant candidates.Semantic proximity Read ↗

Tumor-reactive T-cells accumulate in lung cancer tissues but fail to respond due to tumor cell-derived factor.Semantic proximity Read ↗

Cellular interaction against autologous tumor cells between IL-2-cultured lymphocytes and fresh peripheral blood lymphocytes in patients with breast cancer given immuno-chemotherapy.Semantic proximity Read ↗

Generation and characterization of lymphokine-activated killer cells from non-Hodgkin's lymphoma patients.Semantic proximity Read ↗

Autologous tumor cell killing activity of tumor-associated lymphocytes in patients with head and neck carcinomas.Semantic proximity Read ↗

Adoptively transferred human lung tumor specific cytotoxic T cells can control autologous tumor growth and shape tumor phenotype in a SCID mouse xenograft model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.