Article
Genotypic impact of prolonged detectable HIV type 1 RNA viral load after HAART failure in a CRF01_AE-infected cohort.
AIDS research and human retroviruses - 1 Jul 2011
Zolfo Maria, Schapiro Jonathan M, Phan Vichet, Koole Olivier, Thai Sopheak, Vekemans Marc, Fransen Katrien, Lynen Lutgarde
Abstract excerpt
HIV subtype-specific data on mutation type, rate, and accumulation following HAART treatment failure are limited. We studied patterns and accrual of drug resistance mutations in a Cambodian CRF01_AE-infected cohort continuing a virologically failing first-line, nonnucleoside reverse transcriptase inhibitor- (NNRTI-) based, HAART. Between 2005 and 2007, 837 adult HIV-infected patients had regular plasma HIV-1 RNA...
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