Article
Low prevalence of drug resistance transmitted virus in HIV Type 1-infected ARV-naive patients in Cambodia.
AIDS research and human retroviruses - 1 May 2009
Nouhin Janin, Ngin Sopheak, Martin P Regis, Marcy Olivier, Kruy Leangsim, Ariey Frederic, Peeters Martine, Chaix Marie-Laure, Ayouba Ahidjo, Nerrienet Eric
Abstract excerpt
Abstract Between November 2006 and June 2007, HIV-1 reverse transcriptase (RT) and protease (PR) genes of 67 ARV-naive Cambodian patients were amplified and sequenced. At inclusion, the median age and duration of HIV infection were 28 and 1.1 years, respectively. The median CD4 and HIV-1 RNA were 611 cells/ml [IQR: 525-759] and 4.0 log(10) copies/ml [IQR: 3.4-4.6]. Among 67 HIV-1 strains, 95.5% were CRF 01_AE...
Topics
- Adult
- Amino Acid Substitution
- CD4 Lymphocyte Count
- Cambodia
- Drug Resistance, Viral
- Female
- Genotype
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Male