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Article

Accumulation of HIV drug resistance mutations in patients failing first-line antiretroviral treatment in South Africa.

AIDS research and human retroviruses - 1 Feb 2012

Sigaloff Kim C E, Ramatsebe Tina, Viana Raquel, de Wit Tobias F Rinke, Wallis Carole L, Stevens Wendy S

Abstract excerpt

Patients failing antiretroviral treatment for extended periods of time are at risk of accumulating HIV drug resistance mutations (DRMs), which negatively influences second-line treatment. This retrospective study assessed the rate of DRM accumulation among South African patients with continued virological failure. Serial genotypic resistance testing was performed and DRMs were scored according to the 2009 IAS-USA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21819219
DOI: 10.1089/aid.2011.0136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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