Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance-associated mutations after initial antiretroviral treatment failure in a large cohort of patients infected with HIV-1 subtype CRF01_AE.

Current HIV research - 1 Dec 2012

Praparattanapan Jutarat, Kotarathitithum Wilai, Chaiwarith Romanee, Nuntachit Nontakan, Sirisanthana Thira, Supparatpinyo Khuanchai

Abstract excerpt

The nucleoside reverse transcriptase inhibitors (NRTIs), zidovudine (AZT) and stavudine (d4T) are thymidine analog drugs recommended as first-line antiretroviral therapy in HIV-1-naive patients. Two thymidine analog mutation (TAM) pathways, TAM-1 and TAM-2, confer high levels of resistance with mutations in the viral RT. The relative prevalence of TAM pathways and their associations with other NRTI resistance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Multiple, Viral
Share to HIV Reverse Transcriptase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Reverse Transcriptase Inhibitors

Share to Stavudine

Share to Thailand

Share to Thymidine

Share to Treatment Failure

Share to Zidovudine

Source

Identifiers

PMID: 23061604
DOI: 10.2174/157016212803901356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance-associated mutations after initial antiretroviral treatment failure in a large cohort of patients infected with HIV-1 subtype CRF01_AE.PMID 23061604Read ↗

Patterns of HIV-1 Drug Resistance After First-Line Antiretroviral Therapy (ART) Failure in 6 Sub-Saharan African Countries: Implications for Second-Line ART StrategiesSemantic proximity Read ↗

Incidence of HIV-1 drug resistance among antiretroviral treatment-naive individuals starting modern therapy combinations.Semantic proximity Read ↗

Frequency and treatment-related predictors of thymidine-analogue mutation patterns in HIV-1 isolates after unsuccessful antiretroviral therapy.Semantic proximity Read ↗

In-depth analysis of HIV-1 drug resistance mutations in HIV-infected individuals failing first-line regimens in West and Central Africa.Semantic proximity Read ↗

Spectrum of Atazanavir-Selected Protease Inhibitor-Resistance MutationsSemantic proximity Read ↗

HIV-1 drug-resistance patterns among patients on failing treatment in a large number of European countries.Semantic proximity Read ↗

Etravirine and rilpivirine resistance in HIV-1 subtype CRF01_AE-infected adults failing non-nucleoside reverse transcriptase inhibitor-based regimens.Semantic proximity Read ↗

Impact of the number of failed therapeutic regimes on the development of resistance mutations to HIV-1 in northeast Brazil.Semantic proximity Read ↗

Antiretroviral Resistance After First-Line Antiretroviral Therapy Failure in Diverse HIV-1 Subtypes in the SECOND-LINE Study.Semantic proximity Read ↗

Thymidine analogue reverse transcriptase inhibitors resistance mutations profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure.Semantic proximity Read ↗

Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis.Semantic proximity Read ↗

Drug resistance mutations and genetic diversity in adults treated for HIV type 1 infection in Mauritania.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.