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Article

Drug Susceptibility and Resistance Mutations After First-Line Failure in Resource Limited Settings

1 May 2014

Abstract excerpt

BACKGROUND: The development of drug resistance to nucleoside reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) has been associated with baseline human immunodeficiency virus (HIV)-1 RNA level (VL), CD4 cell counts (CD4), subtype, and treatment failure duration. This study describes drug resistance and levels of susceptibility after first-line virologic failure in...

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PMID: 24795328
DOI: 10.1093/cid/ciu314

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