Article
Association of IL-2RA/CD25 with type 1 diabetes in the Belgian population.
Human immunology - 1 Dec 2010
Aminkeng Folefac, Weets Ilse, Van Autreve Jan E, Koeleman Bobby P C, Quartier Erik, Van Schravendijk Chris, Gorus Frans K, Van der Auwera Bart J R
Abstract excerpt
Our goals were to study the proposed association of IL-2RA /CD25 with type 1 diabetes in the Belgian population over a broad age range, and to explore possible correlations with disease phenotypes, immune markers, HLA-DQ, INS, and PTPN22. Patients (n = 1954), healthy controls (n = 2082), and families (n = 420) were genotyped for IL-2RA/CD25 rs41295061(C>A), HLA-DQ, INS-VNTR and PTPN22. IL-2RA/CD25 was associated...
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