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Article

Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population.

The Journal of clinical endocrinology and metabolism - 1 Mar 2009

Kawasaki Eiji, Awata Takuya, Ikegami Hiroshi, Kobayashi Tetsuro, Maruyama Taro, Nakanishi Koji, Shimada Akira, Uga Miho, Kurihara Susumu, Kawabata Yumiko, Tanaka Shoichiro, Kanazawa Yasuhiko, Eguchi Katsumi

Abstract excerpt

CONTEXT/OBJECTIVE: The IL-2 receptor-alpha (IL2RA), also known as CD25, is expressed on the regulatory T cells, which play an important role in the control of immune responses and the maintenance of immune homeostasis. Our objective was to determine whether variants in the IL2RA gene are associated with type 1 diabetes in the Japanese population. DESIGN/PATIENTS: We genotyped the four single-nucleotide...

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Share to Diabetes Mellitus, Type 1
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class II

Share to Interleukin-2 Receptor alpha Subunit

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 19106270
DOI: 10.1210/jc.2008-1596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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