Article
Anti-inflammatory action of donepezil ameliorates tau pathology, synaptic loss, and neurodegeneration in a tauopathy mouse model.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Yoshiyama Yasumasa, Kojima Ayako, Ishikawa Chieko, Arai Kimihito
Abstract excerpt
Acetylcholinesterase inhibitors (AChEIs) are widely used to compensate for acetylcholine (ACh) depletion in the Alzheimer's disease (AD) brain. Some clinical and experimental studies, however, have suggested that AChEIs also provide neuroprotection. To assess the effect of AChEIs on neurodegenera...
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