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Article

A pyrosequencing-based assay for the rapid detection of IDH1 mutations in clinical samples.

The Journal of molecular diagnostics : JMD - 1 Nov 2010

Setty Prashanth, Hammes Jennifer, Rothämel Thomas, Vladimirova Valentina, Kramm Christof M, Pietsch Torsten, Waha Andreas

Abstract excerpt

Mutations of both the IDH1 and IDH2 (isocitratedehydrogenase enzyme 1 and 2) genes have recently been described in cases of human glioma. Since IDH1 mutations have been associated with better clinical outcome, they are suitable predictive markers for adult glioma patients. We have developed a pyr...

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Source

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Identifiers

PMID: 20847279
DOI: 10.2353/jmoldx.2010.090237
PMCID: PMC2963913

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20847279-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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