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Article

Pyrosequencing of IDH1 and IDH2 mutations in brain tumors and non-neoplastic conditions.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 2012

Cykowski Matthew D, Allen Richard A, Fung Kar-Ming, Harmon Michael A, Dunn Samuel T

Abstract excerpt

The molecular profiling of brain tumors, including testing for MGMT promoter methylation and chromosome 1p/19q deletion, can provide both diagnostic and prognostic information that may guide treatment. Isocitrate dehydrogenase (IDH) mutation testing is a recent addition to this armamentarium of molecular pathology tools that similarly provides both diagnostic (eg, glioma vs. gliosis) and prognostic information....

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Source

Identifiers

PMID: 23111198
DOI: 10.1097/PDM.0b013e31825d802b

Genes

IDH1
IDH2
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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