Article
Thrombospondin-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylation.
BMC cancer - 16 Sept 2010
Greco Sonia A, Chia June, Inglis Kelly J, Cozzi Sarah-Jane, Ramsnes Ingunn, Buttenshaw Ronald L, Spring Kevin J, Boyle Glen M, Worthley Daniel L, Leggett Barbara A, Whitehall Vicki L J
Abstract excerpt
BACKGROUND: Thrombospondin-4 (THBS4) is a member of the extracellular calcium-binding protein family and is involved in cell adhesion and migration. The aim of this study was to evaluate the potential role of deregulation of THBS4 expression in colorectal carcinogenesis. Of particular interest wa...
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