BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma.

doi:10.1172/JCI44228

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma.

The Journal of clinical investigation - 1 Oct 2011

Williams Christopher S, Zhang Baolin, Smith J Joshua, Jayagopal Ashwath, Barrett Caitlyn W, Pino Christopher, Russ Patricia, Presley Sai H, Peng DunFa, Rosenblatt Daniel O, Haselton Frederick R, Yang Jin-Long, Washington M Kay, Chen Xi, Eschrich Steven, Yeatman Timothy J, El-Rifai Wael, Beauchamp R Daniel, Chang Min S

Abstract excerpt

The acquisition of a mesenchymal phenotype is a critical step in the metastatic progression of epithelial carcinomas. Adherens junctions (AJs) are required for suppressing this epithelial-mesenchymal transition (EMT) but less is known about the role of tight junctions (TJs) in this process. Here, we investigated the functions of blood vessel epicardial substance (BVES, also known as POPDC1 and POP1), an integral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adherens Junctions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Adhesion Molecules

Share to Colonic Polyps

Share to Epithelial-Mesenchymal Transition

Share to Epithelium, Corneal

Share to Neoplasm Transplantation

Share to Tight Junctions

Share to Transplantation, Heterologous

Source

Open in PubMed Open full text

Identifiers

PMID: 21911938
DOI: 10.1172/JCI44228
PMCID: PMC3195453

Genes

POP1
POPDC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma.PMID 21911938Read ↗

BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesisSemantic proximity Read ↗

The role of Popeye domain-containing protein 1 (POPDC1) in the progression of the malignant phenotype.Semantic proximity Read ↗

Shedding light on the EpCAM: An overviewSemantic proximity Read ↗

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.Semantic proximity Read ↗

Functions of EpCAM in physiological processes and diseases (Review)Semantic proximity Read ↗

Genes regulating membrane-associated E-cadherin and proliferation in adenomatous polyposis coli mutant colon cancer cells: High content siRNA screen.Semantic proximity Read ↗

Defective Claudin-7 Regulation by Tcf-4 and Sox-9 Disrupts the Polarity and Increases the Tumorigenicity of Colorectal Cancer CellsSemantic proximity Read ↗

SPARC inhibits epithelial cell proliferation in part through stimulation of the transforming growth factor-beta-signaling system.Semantic proximity Read ↗

Claudin-4 Overexpression in Epithelial Ovarian Cancer Is Associated with Hypomethylation and Is a Potential Target for Modulation of Tight Junction Barrier Function Using a C-Terminal Fragment of Clostridium perfringens EnterotoxinSemantic proximity Read ↗

DMBT1 expression and glycosylation during the adenoma-carcinoma sequence in colorectal cancer.Semantic proximity Read ↗

Crucial Roles of Sp1 and Epigenetic Modifications in the Regulation of the CLDN4 Promoter in Ovarian Cancer CellsSemantic proximity Read ↗

The role of MMP-9 in the anti-angiogenic effect of secreted protein acidic and rich in cysteineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.