Article
Oxidative stress status, clinical outcome, and β‐globin gene cluster haplotypes in pediatric patients with sickle cell disease
16 Sept 2010
Abstract excerpt
OBJECTIVE: To correlate the clinical and hematological features of β-globin gene haplotypes with the oxidative stress status in pediatric patients with sickle cell disease (SCD). METHODS: A total of 95 patients with SCD and 40 healthy children were studied. The β-globin cluster, plasma lipid peroxidation (LPO) and plasma nitrite plus nitrate (NOx), and erythrocyte content of glutathione (GSH) and glutathione...
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