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Redox Balance in β-Thalassemia and Sickle Cell Disease: A Love and Hate Relationship

13 May 2022

Abstract excerpt

β-thalassemia and sickle cell disease (SCD) are inherited hemoglobinopathies that result in both quantitative and qualitative variations in the β-globin chain. These in turn lead to instability in the generated hemoglobin (Hb) or to a globin chain imbalance that affects the oxidative environment both intracellularly and extracellularly. While oxidative stress is not among the primary etiologies of β-thalassemia...

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PMID: 35624830
DOI: 10.3390/antiox11050967

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