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Article

Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation.

Genes & development - 1 Oct 2010

Singh Jaskirat, Yanfeng Wang A, Grumolato Luca, Aaronson Stuart A, Mlodzik Marek

Abstract excerpt

Abelson (Abl) family tyrosine kinases have been implicated in cell morphogenesis, adhesion, motility, and oncogenesis. Using a candidate approach for genes involved in planar cell polarity (PCP) signaling, we identified Drosophila Abl (dAbl) as a modulator of Frizzled(Fz)/PCP signaling. We demons...

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Share to Frizzled Receptors
Share to Adaptor Proteins, Signal Transducing
Share to Cell Polarity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dishevelled Proteins

Share to Phosphoproteins

Share to Photoreceptor Cells, Invertebrate

Share to Protein-Tyrosine Kinases

Share to Receptors, G-Protein-Coupled

Source

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Identifiers

PMID: 20837657
DOI: 10.1101/gad.1961010
PMCID: PMC2947768

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20837657-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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