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Article

Abl regulates planar polarized junctional dynamics through β-catenin tyrosine phosphorylation.

Developmental cell - 14 Feb 2012

Tamada Masako, Farrell Dene L, Zallen Jennifer A

Abstract excerpt

Interactions between epithelial cells are mediated by adherens junctions that are dynamically regulated during development. Here we show that the turnover of β-catenin is increased at cell interfaces that are targeted for disassembly during Drosophila axis elongation. The Abl tyrosine kinase is concentrated at specific planar junctions and is necessary for polarized β-catenin localization and dynamics. abl mutant...

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Identifiers

PMID: 22340496
DOI: 10.1016/j.devcel.2011.12.025
PMCID: PMC3327890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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