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Article

Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis.

BMC genomics - 10 Sept 2010

Batenchuk Cory, Tepliakova Lioudmila, Kaern Mads

Abstract excerpt

BACKGROUND: High-throughput genomics has enabled the global mapping of genetic interactions based on the phenotypic impact of combinatorial genetic perturbations. An important next step is to understand how these networks are dynamically remodelled in response to environmental stimuli. Here, we report on the development and testing of a method to identify such interactions. The method was developed from first...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20831804
DOI: 10.1186/1471-2164-11-493
PMCID: PMC2996989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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