Article
Estrogen receptor alpha gene polymorphism associated with type 2 diabetes mellitus and the serum lipid concentration in Chinese women in Guangzhou.
Chinese medical journal - 5 Nov 2006
Huang Qin, Wang Ting-huai, Lu Wen-sheng, Mu Pan-wei, Yang Yan-fang, Liang Wei-wen, Li Cai-xia, Lin Gui-ping
Abstract excerpt
BACKGROUND: Estrogen might play an important role in type 2 diabetes mellitus pathogenesis. A number of polymorphisms have been reported in the estrogen receptor alpha (ERalpha) gene (also named ESR1), including the XbaI and PvuII restriction enzyme polymorphisms of ESR1, which may be involved in disease pathogenesis. The aim of this study was to determine whether ERX gene polymorphisms are associated with type 2...
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