Article
Microarray for hepatitis B virus genotyping and detection of 994 mutations along the genome.
Journal of clinical microbiology - 1 Nov 2010
Gauthier Marie, Bonnaud Bertrand, Arsac Maud, Lavocat Fabien, Maisetti Jérôme, Kay Alan, Simon François, Zoulim Fabien, Vernet Guy
Abstract excerpt
Genome analysis of hepatitis B virus (HBV) in patient sera is helpful for monitoring treatment. We developed an improved version of a DNA microarray to identify HBV genotypes and to detect mutations of interest in the S, Pol, Core, and X genes. It includes an automated software analysis of fluorescence values for simpler, more robust data interpretation. In this version, probes were added to identify genotype H,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
