Article
Genetic variability of the S gene of hepatitis B virus: clinical and diagnostic impact.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Feb 2005
Weber Bernard
Abstract excerpt
The genetic variability of hepatitis B virus (HBV) represents a challenge for the sensitivity of immunologic and molecular based assays. Based on sequence divergence in the entire genome of >8%, HBV genomes have been classified into eight groups designated A to H. The genotypes of HBV have distinct geographical distributions. Although preliminary clinical studies seem to indicate that there is an association...
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