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Article

Rapid high-throughput genotyping of HBV DNA using a modified hybridization-extension technique.

Physical chemistry chemical physics : PCCP - 7 Nov 2013

Bao Han, Zhao Wenliang, Ruan Banjun, Wang Qing, Zhao Jinrong, Lei Xiaoying, Wang Weihua, Liu Yonglan, Sun Jianbing, Xiang An, Guo Yanhai, Yan Zhen

Abstract excerpt

China has the highest incidence of hepatitis B virus (HBV) infection worldwide. HBV genotypes have variable impacts on disease pathogenesis and drug tolerance. We have developed a technically simple and accurate method for HBV genotyping that will be applicable to pre-treatment diagnosis and individualized treatment. Multiple sequence alignments of HBV genomes from GenBank were used to design primers and probes...

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PMID: 24065125
DOI: 10.1039/c3cp51971f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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