Article
Tumour necrosis factor-α promoter region polymorphisms affect the course of spontaneous HBsAg clearance.
Liver international : official journal of the International Association for the Study of the Liver - 1 Nov 2010
Kao Pei-Chi, Wu Jia-Feng, Ni Yen-Hsuan, Lin Ying-Ting, Chen Huey-Ling, Hsu Sandy Huey-Jen, Hsu Hong-Yuan, Chang Mei-Hwei
Abstract excerpt
BACKGROUND: This study aimed to investigate the roles of tumour necrosis factor-α (TNF-α) gene polymorphisms in the spontaneous clearance of HBsAg after a hepatitis B virus (HBV) infection. METHODS: Polymorphisms in the TNF-α (-1031 T to C, -863 C to A, -857 C to T, -308 G to A and -238 G to A transition) gene were evaluated in 274 chronic HBV-infected patients and 194 patients with resolved HBV infection. The...
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