Article
Tumour necrosis factor-α-857T allele reduces the risk of hepatitis B virus infection in an Asian population.
Journal of viral hepatitis - 1 Feb 2012
Shi K-Q, Cai X-H, Xiao D-D, Wu S-J, Peng M-M, Lin X-F, Liu W-Y, Fan Y-C, Chen Y-P, Zheng M-H
Abstract excerpt
Tumour necrosis factor-α (TNF-α) plays a pivotal role in hepatitis B virus (HBV) clearance and host immune response determining the chronicity of HBV infection. However, studies of the association between TNF-α-857 polymorphism and chronic HBV infection have reported conflicting results. So a meta-analysis was carried out to draw a more precise conclusion. Pubmed (January, 1966-March, 2011) and the China...
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