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Gene Expression in Trypanosomatid Parasites

1 Jan 2010

Abstract excerpt

The parasites Leishmania spp., Trypanosoma brucei, and Trypanosoma cruzi are the trypanosomatid protozoa that cause the deadly human diseases leishmaniasis, African sleeping sickness, and Chagas disease, respectively. These organisms possess unique mechanisms for gene expression such as constitutive polycistronic transcription of protein-coding genes and trans-splicing. Little is known about either the DNA...

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PMID: 20169133
DOI: 10.1155/2010/525241

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