Article
Chromatin remodelling during the life cycle of trypanosomatids.
International journal for parasitology - 1 May 2000
Belli S I
Abstract excerpt
The mechanisms which control the expression of developmentally regulated genes in trypanosomatids remain unclear. The genes are grouped together into transcription units that are co-transcribed to yield polycistronic RNAs. Trans-splicing and polyadenylation give rise to mature, monocistronic mRNAs. It is difficult to imagine that expression of these genes is controlled at the level of transcription initiation...
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