Direct activation of human dendritic cells by particle-bound but not soluble MHC class II ligand.

Abstract excerpt

Dendritic cells (DCs) are key activators of cellular immune responses through their capacity to induce naïve T cells and sustained effector T cell responses. This capacity is a function of their superior efficiency of antigen presentation via MHC class I and class II molecules, and the expression of co-stimulatory cell surface molecules and cytokines. Maturation of DCs is induced by microbial factors via pattern...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Calcium Signaling
• Share to Calmodulin
• Share to Dendritic Cells