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Article

Hepatitis C virus E2 envelope protein induces dendritic cell maturation.

Journal of viral hepatitis - 1 Dec 2007

Zhou Y, Lukes Y, Anderson J, Fileta B, Reinhardt B, Sjogren M

Abstract excerpt

Maturation is a critical process for dendritic cells (DC) to gain or enhance their functions in antigen presentation and T-cell activation. In this study, we investigated the effect of hepatitis C virus (HCV) envelope protein E2 on DC maturation and related functions. We show that binding of E2 protein to DC leads to a change from immature to mature phenotype as detected by an increased expression of cell surface...

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Identifiers

PMID: 18070288
DOI: 10.1111/j.1365-2893.2007.00879.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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