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Article

Hepatitis C virus core protein impairs in vitro priming of specific T cell responses by dendritic cells and hepatocytes.

Journal of hepatology - 1 Jan 2008

Zimmermann Mona, Flechsig Christin, La Monica Nicola, Tripodi Marco, Adler Guido, Dikopoulos Nektarios

Abstract excerpt

BACKGROUND/AIMS: Hepatitis C virus leads to chronic hepatitis in the majority of infected individuals. The mechanism of viral persistence is not completely understood. Hepatitis C virus core protein is produced within hepatocytes and is secreted during HCV infection. Our study characterizes the effects of core protein on T cell priming in mice. METHODS: We used a system of antigen-specific in vitro priming of...

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Identifiers

PMID: 17998148
DOI: 10.1016/j.jhep.2007.08.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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