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Article

Phenotype and functional evaluation of ex vivo generated antigen-specific immune effector cells with potential for therapeutic applications.

Journal of hematology & oncology - 6 Aug 2009

Han Shuhong, Huang Yuju, Liang Yin, Ho Yuchin, Wang Yichen, Chang Lung-Ji

Abstract excerpt

Ex vivo activation and expansion of lymphocytes for adoptive cell therapy has demonstrated great success. To improve safety and therapeutic efficacy, increased antigen specificity and reduced non-specific response of the ex vivo generated immune cells are necessary. Here, using a complete protein-spanning pool of pentadecapeptides of the latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV), a weak viral...

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Source

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Identifiers

PMID: 19660111
DOI: 10.1186/1756-8722-2-34
PMCID: PMC2729746

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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