Article
Role of Toll-Like Receptor 3 Gene Polymorphisms in Preeclampsia.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2015
Chen Aiping, Li Congying, Wang Jingli, Sha Han, Piao Shunfu, Liu Shiguo
Abstract excerpt
BACKGROUND/AIMS: Accumulating evidence suggests that an excessive maternal systemic inflammatory response to pregnancy with exaggerated activation of the innate immune system plays a critical role in the development of preeclampsia (PE). In this study, we investigated whether polymorphisms in the Toll-like receptor 3 (TLR3) gene are associated with susceptibility to PE in the Chinese Han population. METHODS: We...
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