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Article

Toll-like receptor 4 gene polymorphisms and preeclampsia: lack of association in a Caucasian population.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 May 2008

Molvarec Attila, Jermendy Agnes, Kovács Margit, Prohászka Zoltán, Rigó János

Abstract excerpt

Preeclampsia is a multifactorial disorder with genetic and environmental components. As Toll-like receptor 4 (TLR4) has an essential role in innate immune response, which is exaggeratedly activated in preeclampsia, our aim was to investigate whether two single nucleotide polymorphisms (SNPs) of the TLR4 gene--Asp299Gly (A896G) and Thr399Ile (C1196T)--are associated with preeclampsia in a Caucasian population from...

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PMID: 18712040
DOI: 10.1291/hypres.31.859

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TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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