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Article

Association Between TLR4 Gene Polymorphisms and Risk of Preeclampsia: Systematic Review and Meta-Analysis.

Medical science monitor : international medical journal of experimental and clinical research - 2 Aug 2021

Sun Manni, Jiang Hui, Meng Tao, Liu Peiyan, Chen Haiying

Abstract excerpt

BACKGROUND Toll-like receptor 4 (TLR4) plays a pivotal role in the innate immune response and is hyperactivated in preeclampsia (PE). Several researchers have published conflicting evidence for TLR4 rs4986790 and rs4986791 single nucleotide polymorphisms (SNPs) as risk factors for PE. The present meta-analysis was conducted to obtain a more definitive conclusion about the effects of these SNPs on PE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34334784
DOI: 10.12659/MSM.930438
PMCID: PMC8343538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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