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Article

BOOST: A fast approach to detecting gene-gene interactions in genome-wide case-control studies.

American journal of human genetics - 10 Sept 2010

Wan Xiang, Yang Can, Yang Qiang, Xue Hong, Fan Xiaodan, Tang Nelson L S, Yu Weichuan

Abstract excerpt

Gene-gene interactions have long been recognized to be fundamentally important for understanding genetic causes of complex disease traits. At present, identifying gene-gene interactions from genome-wide case-control studies is computationally and methodologically challenging. In this paper, we introduce a simple but powerful method, named "BOolean Operation-based Screening and Testing" (BOOST). For the discovery...

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Identifiers

PMID: 20817139
DOI: 10.1016/j.ajhg.2010.07.021
PMCID: PMC2933337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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